Aromatase (CYP19A1) Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12238-20, A12238-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
Synonyms: ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM; Aromatase (CYP19A1)
GeneID: 1588
Swiss Prot: P11511
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human
Calculated Molecular Weight: 58kDa
Observed Molecular Weight: 58kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aromatase (CYP19A1) (P11511).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Cancer, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Endocrine Metabolism, Lipid Metabolism, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87MG
Cellular Location: Endoplasmic Reticulum
Keywords: CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM, cytochrome P450 family 19 subfamily A member 1, aromatase|cytochrome P-450AROM|cytochrome P450 19A1|cytochrome P450, family 19, subfamily A, polypeptide 1|cytochrome P450, subfamily XIX (aromatization of androgens)|estrogen synthase|estrogen synthetase|flavoprotein-linked monooxygenase|microsomal monooxygenase, P11511, Aromatase (CYP19A1)
Symbol: CYP19A1
Category: Monoclonal Antibodies
Research Use Only