BRD4 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12677-20, A12677-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Synonyms: CAP; MCAP; HUNK1; HUNKI; FSHRG4; BRD4
GeneID: 23476
Swiss Prot: O60885
Tested Applications: ELISA, WB, IHC-P
Reactivity: Human
Calculated Molecular Weight: 152kDa
Observed Molecular Weight: 120kDa/140kDa/200kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human BRD4 (O60885).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor suppressors, Signal Transduction, Kinase, Serine threonine kinases
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Jurkat
Cellular Location: Chromosome, Nucleus
Keywords: BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4, bromodomain-containing protein 4|chromosome-associated protein, O60885
Symbol: BRD4
Category: Monoclonal Antibodies
Research Use Only