Dot1L/KMT4 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12329-20, A12329-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Synonyms: DOT1; KMT4; Dot1L/KMT4
GeneID: 84444
Swiss Prot: Q8TEK3
Tested Applications: ELISA, WB, IP
Reactivity: Human, Mouse
Calculated Molecular Weight: 165kDa
Observed Molecular Weight: 170kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Dot1L/KMT4 (NP_115871.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, DNA Damage Repair
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, U-87MG, Mouse brain
Cellular Location: Nucleus
Keywords: DOT1L, DOT1, KMT4, DOT1 like histone lysine methyltransferase, histone-lysine N-methyltransferase, H3 lysine-79 specific|DOT1 like histone H3K79 methyltransferase|DOT1-like histone methyltransferase|DOT1-like protein|DOT1-like, histone H3 methyltransferase|H3-K79-HMTase|histone H3-K79 methyltransferase|histone methyltransferase DOT1L|lysine N-methyltransferase 4, Q8TEK3, Dot1L/KMT4
Symbol: DOT1L
Category: Monoclonal Antibodies
Research Use Only