HDAC4 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13510-20, A13510-100
Citations, Manuals and SDS Available upon request.
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Synonyms: HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; NEDCHF; NEDCHID; HDAC4
GeneID: 9759
Swiss Prot: P56524
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 119kDa
Observed Molecular Weight: 140kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC4 (P56524).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G1 S Checkpoint, Wnt /β-Catenin Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells, Cardiovascular, Heart, Hypertrophy
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Jurkat, THP-1
Cellular Location: Cytoplasm, Nucleus
Keywords: HDAC4, AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, histone deacetylase 4, histone deacetylase 4|histone deacetylase A, P56524
Symbol: HDAC4
Category: Monoclonal Antibodies
Research Use Only