HDAC7 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13008-20, A13008-100
Citations, Manuals and SDS Available upon request.
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: HD7; HD7A; HDAC7A; HDAC7
GeneID: 51564
Swiss Prot: Q8WUI4
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 103kDa
Observed Molecular Weight: 90-130kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-198 of human HDAC7 (Q8WUI4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G1 S Checkpoint, Wnt ��-Catenin Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells, Cardiovascular, Heart, Hypertrophy
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, K-562, Mouse lung, Mouse brain, Mouse heart, Rat testis
Cellular Location: Cytoplasm, Nucleus
Keywords: HDAC7, HD7, HD7A, HDAC7A, histone deacetylase 7, histone deacetylase 7|histone deacetylase 7A, Q8WUI4
Symbol: HDAC7
Category: Monoclonal Antibodies
Research Use Only