LGR5/GPR49 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12327-20, A12327-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms: FEX; HG38; GPR49; GPR67; GRP49; LGR5/GPR49
GeneID: 8549
Swiss Prot: O75473
Tested Applications: ELISA, WB
Reactivity: Mouse, Rat
Calculated Molecular Weight: 100kDa
Observed Molecular Weight: 110kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800-907 of human LGR5/GPR49 (O75473).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse ovary, Mouse brain, Rat testis, Rat brain
Cellular Location: Cell Membrane, Golgi Apparatus, Multi-pass Membrane Protein, Trans-Golgi Network Membrane,
Keywords: LGR5, FEX, GPR49, GPR67, GRP49, HG38, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5|G-protein coupled receptor 49|G-protein coupled receptor 67|G-protein coupled receptor HG38|orphan G protein-coupled receptor HG38, O75473, LGR5/GPR49
Symbol: LGR5
Category: Monoclonal Antibodies
Research Use Only