MAP1LC3A Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12319-20, A12319-100
Citations, Manuals and SDS Available upon request.
Background: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Synonyms: LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3; MAP1LC3A
GeneID: 84557
Swiss Prot: Q9H492
Tested Applications: ELISA, WB, IP
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 14kDa
Observed Molecular Weight: 14kDa, 16kDa/16kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP1LC3A (Q9H492).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Research Areas: Cancer, Cell Biology Developmental Biology, Autophagy, Cytoskeleton, Microtubules, Endocrine Metabolism, Mitochondrial metabolism, Cardiovascular, Heart
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: NIH/3T3, C6, SH-SY5Y
Cellular Location: Cytoplasm, Cytoplasmic Vesicle, EndoMembrane System, Lipid-anchor, Autophagosome, Autophagosome Membrane, Cytoskeleton,
Keywords: MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha, microtubule-associated proteins 1A/1B light chain 3A|MAP1 light chain 3-like protein 1|MAP1A/1B light chain 3 A|MAP1A/MAP1B LC3 A|MAP1A/MAP1B light chain 3 A|autophagy-related ubiquitin-like modifier LC3 A|microtubule-associated proteins 1A/1B light chain 3, Q9H492
Symbol: MAP1LC3A
Category: Monoclonal Antibodies
Research Use Only