MEK5 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12457-20, A12457-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Synonyms: MEK5
GeneID: 5607
Swiss Prot: Q13163
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 50kDa
Observed Molecular Weight: 50kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MEK5 (Q13163).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, Serine threonine kinases, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Cytoskeleton, Actins, Immunology Inflammation, Jak-Stat-IL-6 Receptor Signaling Pathway, Cardiovascular, Heart, Cardiogenesis
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse testis, Rat liver, RD
Cellular Location: Cytosol, Nucleus, Spindle
Keywords: MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5, dual specificity mitogen-activated protein kinase kinase 5|MAP kinase kinase 5|MAP kinase kinase MEK5b|MAPK/ERK kinase 5|MAPKK 5|MEK 5, Q13163
Symbol: MAP2K5
Category: Monoclonal Antibodies
Research Use Only