MERTK Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12294-20, A12294-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Synonyms: MER; RP38; c-Eyk; c-mer; Tyro12; MERTK
GeneID: 10461
Swiss Prot: Q12866
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 110kDa
Observed Molecular Weight: 150-200kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MERTK (Q12866).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Hep G2
Cellular Location: Cell Membrane, Single-pass Type I Membrane Protein
Keywords: MERTK, MER, RP38, Tyro12, c-Eyk, c-mer, MER proto-oncogene, tyrosine kinase, tyrosine-protein kinase Mer|MER receptor tyrosine kinase|STK kinase|c-mer proto-oncogene tyrosine kinase|proto-oncogene c-Mer|receptor tyrosine kinase MerTK, Q12866
Symbol: MERTK
Category: Monoclonal Antibodies
Research Use Only