PGK1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12686-20, A12686-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
Synonyms: PGKA; MIG10; HEL-S-68p; PGK1
GeneID: 5230
Swiss Prot: P00558
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 45kDa
Observed Molecular Weight: 45kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PGK1 (P00558).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Cancer, Signal transduction, Endocrine metabolism, Carbohydrate metabolism, Cardiovascular, Blood
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, HepG2, K-562, Mouse lung, Mouse brain, Rat ovary, Rat kidney
Cellular Location: Cytoplasm
Keywords: PGK1, HEL-S-68p, MIG10, PGKA, phosphoglycerate kinase 1, phosphoglycerate kinase 1|PRP 2|cell migration-inducing gene 10 protein|epididymis secretory sperm binding protein Li 68p|primer recognition protein 2, P00558
Symbol: PGK1
Category: Monoclonal Antibodies
Research Use Only