PI3 Kinase p110 beta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1271-20, A1271-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Synonyms: PI3K; PIK3C1; P110BETA; PI3KBETA; PI3 Kinase p110 beta
GeneID: 5291
Swiss Prot: P42338
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 123kDa
Observed Molecular Weight: 110kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PI3 Kinase p110 beta (NP_006210.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Signal Transduction, Kinase, PI3K-Akt Signaling Pathway, mTOR Signaling Pathway, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Cell Cycle, Cell Adhesion, Cytoskeleton, Microtubules, Actins, TGF-b-Smad Signaling Pathway, ESC Pluripotency and Differentiation, Endocrine Metabolism, Lipid Metabolism, AMPK Signaling Pathway, Warburg Effect, Immunology Inflammation, B Cell Receptor Signaling Pathway, T Cell Receptor Signaling Pathway, Jak-Stat-IL-6 Receptor Signaling Pathway, NF-kB Signaling Pathway, Toll-like Receptor Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, TLR Signaling, Cardiovascular, Angiogenesis
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A-549, MCF7
Cellular Location: Cytoplasm, Cytosol, Nucleolus, Nucleoplasm, Nucleus, Plasma Membrane
Keywords: PIK3CB, P110BETA, PI3K, PI3KBETA, PIK3C1, phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit beta, phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit beta isoform|PI3-kinase p110 subunit beta|PI3-kinase subunit beta|PI3K-beta|PtdIns-3-kinase p110|phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta|phosphoinositide-3-kinase, catalytic, beta polypeptide|ptdIns-3-kinase subunit beta|ptdIns-3-kinase subunit p110-beta, P42338, PI3 Kinase p110 beta
Symbol: PIK3CB
Category: Monoclonal Antibodies
Research Use Only