RAB7 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12308-20, A12308-100
Citations, Manuals and SDS Available upon request.
Background: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Synonyms: RAB7; CMT2B; PRO2706
GeneID: 7879
Swiss Prot: P51149
Tested Applications: ELISA, WB, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 23kDa
Observed Molecular Weight: 23kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 108-207 of human RAB7 (NP_004628.4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Signal Transduction, G protein signaling, Small G proteins
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, A549, RD, Mouse kidney, Mouse heart, Rat liver, Rat lung, Rat heart
Cellular Location: Cytoplasmic Side, Cytoplasmic Vesicle, Late Endosome Membrane, Lipid droplet, Lysosome Membrane, Melanosome Membrane, Peripheral Membrane Protein, Autophagosome Membrane, phagosome Membrane,
Keywords: RAB7A, PRO2706, RAB7, member RAS oncogene family, ras-related protein Rab-7a|RAB7, member RAS oncogene family|Ras-associated protein RAB7, P51149, marker, Endosomes, Endosomes marker
Symbol: RAB7A
Category: Monoclonal Antibodies
Research Use Only