SOD1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12537-20, A12537-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Synonyms: ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer; SOD1
GeneID: 6647
Swiss Prot: P00441
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 16kDa
Observed Molecular Weight: 16kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2-154 of human SOD1 (NP_000445.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, 293T, MCF7, Mouse liver, Mouse ovary, Mouse brain, Rat lung, Rat liver, Rat brain
Cellular Location: Cytoplasm, Nucleus
Keywords: SOD1, ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer, superoxide dismutase 1, superoxide dismutase [Cu-Zn]|Cu/Zn superoxide dismutase|SOD, soluble|epididymis secretory protein Li 44|indophenoloxidase A|superoxide dismutase 1, soluble|superoxide dismutase, cystolic, P00441
Symbol: SOD1
Category: Monoclonal Antibodies
Research Use Only