Thymidine Kinase 1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13612-20, A13612-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
Synonyms: TK2; Thymidine Kinase 1
GeneID: 7083
Swiss Prot: P04183
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 25kDa
Observed Molecular Weight: 26kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thymidine Kinase 1 (P04183).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Kinase
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, 293T, Jurkat
Cellular Location: Cytoplasm
Keywords: TK1, TK2, thymidine kinase 1, thymidine kinase, cytosolic|thymidine kinase 1 soluble isoform, P04183, Thymidine Kinase 1
Symbol: TK1
Category: Monoclonal Antibodies
Research Use Only