CYP1B1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1377-20, A1377-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Synonyms: CP1B; ASGD6; GLC3A; CYPIB1; P4501B1; CYP1B1
GeneID: 1545
Swiss Prot: Q16678
Tested Applications: ELISA, WB, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 61kDa
Observed Molecular Weight: 60kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CYP1B1 (NP_000095.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Drug metabolism, Neuroscience, Cardiovascular, Lipids
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A-549, MCF7, HL-60, HT-29, Mouse kidney, Mouse heart, Rat liver
Cellular Location: Endoplasmic Reticulum Membrane, Microsome Membrane, Mitochondrion, Peripheral Membrane Protein,
Keywords: 1545, sc-32882, sc-133490, CP1B, CYP1B1, CYPIB1, Cytochrome P450 1B1, GLC3A, P4501B1, ASGD6, cytochrome P450 family 1 subfamily B member 1, cytochrome P450 1B1, aryl hydrocarbon hydroxylase, cytochrome P450, family 1, subfamily B, polypeptide 1, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile), flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase, Q16678, Cytochrome P450 Family 1 Subfamily B Member 1, Cytochrome P450, Subfamily I (Dioxin-Inducible), Polypeptide 1 (Glaucoma 3, Primary Infantile), Family 1, Subfamily B, Polypeptide 1, Flavoprotein-Linked Monooxygenase, Dioxin-Inducible Cytochrome P450, Aryl Hydrocarbon Hydroxylase, Microsomal Monooxygenase, Xenobiotic Monooxygenase, EC 1.14.14.1, sc32882, sc 32882, sc133490, sc 133490
Symbol: CYP1B1
Category: Polyclonal Antibodies
Research Use Only