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Histone H2A.1 Rabbit pAb - A9895

Histone H2A.1 Rabbit pAb - A9895

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$128.00 USD
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Histone H2A.1 Rabbit pAb

Sizes: 20µl, 100µl

Catalogue Numbers: A9895-20, A9895-100

Citations, Manuals and SDS Available upon request.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Synonyms: H2A/c; H2AFC; H2AC11; H2AC15; H2AC16; H2AC17; HIST1H2AI; Histone H2A.1

GeneID: 3012/8329

Swiss-Prot: P04908/P0C0S8

Reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)

Calculated Molecular Weight: 14kDa

Observed Molecular Weight: 14kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human Histone H2A.1 (NP_064707.1).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Tested Applications: ELISA, WB, IHC-P

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.

Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200

Research Areas: Epigenetics Nuclear Signaling

Modifications: Unmodified

Conjugate: Unconjugated

Positive Samples: MCF7, SW480, A-549, HeLa, K-562, Mouse heart, Mouse intestine

Cellular Location: Chromosome, Nucleus

Category: Polyclonal Antibodies

Citations, Manuals and SDS Available upon request.