FAM3B Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-11214-60, E-AB-11214-120, E-AB-11214-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: FAM3B
Target Synonym: 2-21; C21orf11; C21orf76; Cytokine like protein 2 21; Cytokine-like protein 2-21; Fam3b; FAM3B; Family with sequence similarity 3 member B; ORF9; Pancreatic-derived factor; PANDER; PRED44; Protein FAM3B
Research Areas: Metabolism, Immunology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P58499
Background: FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
Concentration: 0.7 mg/mL
Immunogen: Recombinant protein of human FAM3B
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only