{"title":"Cytokines","description":"","products":[{"product_id":"recombinant-human-epidermal-growth-factor-rhuegf-pr1019","title":"Recombinant Human Epidermal Growth Factor (rHuEGF) - PR1019","description":"\u003cp\u003eRecombinant Human Epidermal Growth Factor (rHuEGF)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1019-100, PR1019-500, PR1019-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 100µg, 500µg, 1.0mg (contact us for the 1.0mg option)\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: 6222 Da, a single non-glycosylated polypeptide chain containing 53 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;98% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as calculated by the dose-dependant proliferation of murine BALB\/c 3T3 cells (measured by 3H-thymidine uptake) is less than 0.1 ng\/ml. , corresponding to a specific activity of \u0026gt; 1.0x 107 units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuEGF as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. Human EGF was isolated from urine based on its inhibitory effect on gastric secretion and named urogastrone, accordingly. EGF is prototypic of a family of growth factors that are derived from membrane-anchored precursors. All members of this family are characterized by the presence of at least one EGF structural unit (defined by the presence of a conserved 6 cysteine motif that forms three disulfide bonds) in their extracellular domain. EGF is initially synthesized as a 130 kDa precursor transmembrane protein containing 9 EGF units. The mature soluble EGF sequence corresponds to the EGF unit located proximal to the transmembrane domain. The membrane EGF precursor is capable of binding to the EGF receptor and was reported to be biologically active.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100µg","offer_id":42880312279219,"sku":"PR1019-100","price":185.88,"currency_code":"USD","in_stock":true},{"title":"500µg","offer_id":42880312311987,"sku":"PR1019-500","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51.jpg?v=1701973209"},{"product_id":"recombinant-murine-epidermal-growth-factor-rmuegf-pr2014","title":"Recombinant Murine Epidermal Growth Factor (rMuEGF ) - PR2014","description":"\u003cp\u003eRecombinant Murine Epidermal Growth Factor (rMuEGF)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR2014-100, PR2014-500, PR2014-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 100µg, 500µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: 6.0 kDa, a single non-glycosylated polypeptide chain containing 53 amino acids, including 3 intramolecular disulfide-bonds.\u003c\/p\u003e\n\u003cp\u003ePurity: 97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as calculated by the dose-dependant proliferation of murine BALB\/c 3T3 cells (measured by 3H-thymidine uptake) is less than 0.1 ng\/ml, corresponding to a specific activity of \u0026gt; 1 x 107 units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rmEGF as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100µg","offer_id":42880312410291,"sku":"PR2014-100","price":185.88,"currency_code":"USD","in_stock":true},{"title":"500µg","offer_id":42880312443059,"sku":"PR2014-500","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_6580fa4a-471c-4ed2-9423-d5b744021796.jpg?v=1701973211"},{"product_id":"recombinant-human-angiostatin-k1-3-pr1001","title":"Recombinant Human Angiostatin K1-3 - PR1001","description":"\u003cp\u003eRecombinant Human Angiostatin K1\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1001-10, PR1001-50, PR1001-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 10µg, 50µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo. The specific activity of anti-migration of endothelial cells in vitro is 0.55×105Units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2μm filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: VYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSP\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/μg of rHuAngiostatin as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: Angiostatin K1-3 is a ~30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10µg","offer_id":42880312508595,"sku":"PR1001-10","price":185.88,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":42880312541363,"sku":"PR1001-50","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e8324a18-5f2d-4f29-b6d7-43514607c2a8.jpg?v=1701973213"},{"product_id":"recombinant-human-baff-receptor-rhubaff-r-pr1003","title":"Recombinant Human BAFF Receptor (rHuBAFF-R) - PR1003","description":"\u003cp\u003eRecombinant Human BAFF Receptor (rHuBAFF-R)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1003-10, PR1003-50, PR1003-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 10µg, 50µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: Approximately 7.7 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;95% by reduced SDS-PAGE analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 1.0-5.0 μg\/ml in the presence of 1.0μg\/ml of human soluble BAFF, corresponding to a Specific Activity of ＞200 IU\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 8.0, 500mM NaCl.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuBAFF-R as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R\/BAFF signaling plays a critical role in B cell survival and maturation.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10µg","offer_id":42880312705203,"sku":"PR1003-10","price":185.88,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":42880312737971,"sku":"PR1003-50","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_273f6b5e-fd62-4644-b472-b7740f6cf967.jpg?v=1701973214"},{"product_id":"recombinant-human-fibroblast-growth-factor-basic-rhubfgf-pr1028","title":"Recombinant Human Fibroblast Growth Factor-basic (rHubFGF ) - PR1028","description":"\u003cp\u003eRecombinant Human Fibroblast Growth Factor-basic (rHubFGF)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1028-10, PR1028-50, PR1028-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 10µg, 50µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: Approximately 17.3 kDa, a single non-glycosylated polypeptide chain containing 155 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is \u0026lt;0.5 ng\/ml, corresponding to a specific activity of 2.0 x 106 Units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGVVSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHubFGF as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: bFGF is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor.Other homologous FGF belonging to the same family are int-2 ( FGF-3 ), FGF-5 , FGF-6 , K-FGF and KGF ( keratinocyte growth factor =FGF-7 ). All factors are products of different genes, some of which are Oncogene products ( FGF-3 , FGF-4 , FGF-5 ).\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10µg","offer_id":42880312836275,"sku":"PR1028-10","price":185.88,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":42880312869043,"sku":"PR1028-50","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0dacf4cd-cdca-4168-ab08-91609636b027.jpg?v=1701973216"},{"product_id":"recombinant-human-fibroblast-growth-factor-acidic-rhuafgf-pr1030","title":"Recombinant Human Fibroblast Growth Factor - acidic (rHuaFGF ) - PR1030","description":"\u003cp\u003eRecombinant Human Fibroblast Growth Factor- acidic (rHuaFGF)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1030-10, PR1030-50, PR1030-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 10µg, 50µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: Approximately 15.8 kDa, a single non-glycosylated polypeptide chain containing 140 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is less than 10 ng\/ml, corresponding to a specific activity of ≥ 1×105 units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDTDGLLYGSQTPNEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHu aFGF as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: FGF acidic, also known as FGF-1 and endothelial cell growth factor, is a member of the FGF family of mitogenic peptides which currently is comprised of at least seven proteins which show 35-55% amino acid sequence conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF acidic has been detected in large amounts in the brain. Other cells known to express FGF acidic include hepatocytes, vascular smooth muscle cells, CNS neurons, skeletal muscle cells, fibroblasts, keratinocytes, endothelial cells, intestinal columnar epithelium cells and pituitary basophils and acidophils. As with other FGF’s, FGF acidic exhibits considerable species crossreactivity. FGF acidic and FGF basic stimulate the proliferation of all cells of mesodermal origin, and many cells of neuroectodermal, ectodermal and endodermal origin.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10µg","offer_id":42880312967347,"sku":"PR1030-10","price":185.88,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":42880313000115,"sku":"PR1030-50","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c97d3bf8-82c0-4d36-8b68-c35ffde5f952.jpg?v=1701973218"},{"product_id":"recombinant-human-interleukin-2-rhuil-2-pr1065","title":"Recombinant Human Interleukin-2 (rHuIL-2) - PR1065","description":"\u003cp\u003eRecombinant Human Interleukin-2 (rHuIL-2)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: PR1065-10, PR1065-50, PR1065-1000\u003c\/p\u003e\n\u003cp\u003eSizes: 10µg, 50µg, 1.0mg \u003cspan data-mce-fragment=\"1\"\u003e(contact us for the 1.0mg option)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: Approximately 15 kDa, a single non-glycosylated polypeptide chain containing 134 amino acids.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is less than 0.1 ng\/ml, corresponding to a specific activity of \u0026gt; 1 x 107 units\/mg.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized from a 0.2m filtered concentrated solution in PBS, pH 7.5.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT\u003c\/p\u003e\n\u003cp\u003eEndotoxin: Less than 1EU\/g of rHuIL-2 as determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\u003cp\u003eDescription: Interleukin 2 is a protein that has a variety of immunologic functions, the most notable being the ability of IL-2 to promote the proliferation and maturation of activated T cells. A comparison of the amino acid sequences of human and murine IL-2 shows an approximately 60% sequence similarity, and human sequence IL-2 has been found to be active on murine cell lines. Some of the biological activities attributed to IL-2 include:\u003cbr\u003e ● induction of secretion of interferon-γ and tumor necrosis factors -α and -β from peripheral blood mononuclear cells\u003cbr\u003e ● stimulation of the rate of synthesis of c-myc RNA and transferrin receptor\u003cbr\u003e ● activation of neutrophils\u003cbr\u003e ● stimulation of proliferation and maturation of activated helper T cells\u003cbr\u003e ● stimulation of proliferation of activated and natural killer cells and tumor-infiltrating lymphocytes, as well as enhancement of the ability of these cytotoxic lymphocytes to kill target cells\u003cbr\u003e ● induction of the expression of IL-2 receptors on T cells\u003cbr\u003e ● stimulation of proliferation of antibody-producing B cells\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10µg","offer_id":42880313131187,"sku":"PR1065-10","price":185.88,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":42880313163955,"sku":"PR1065-50","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fc7f10b9-a550-43a9-b871-9df8b091aeac.jpg?v=1701973220"},{"product_id":"recombinant-human-tnf-α-protein-bk2006","title":"Recombinant Human TNF-α protein - 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BK2008","description":"\u003cp\u003eRecombinant Human IL-6 protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2008-10, BK2008-50, BK2008-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882158592179,"sku":"BK2008-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882158624947,"sku":"BK2008-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882158657715,"sku":"BK2008-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_10e1504d-1926-4f80-97c7-efc820994e01.jpg?v=1702045097"},{"product_id":"recombinant-human-il-2-protein-bk2009","title":"Recombinant Human IL-2 protein - BK2009","description":"\u003cp\u003eRecombinant Human IL-2 protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2009-10, BK2009-50, BK2009-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882158690483,"sku":"BK2009-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882158723251,"sku":"BK2009-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882158756019,"sku":"BK2009-100","price":785.88,"currency_code":"USD","in_stock":true}]},{"product_id":"recombinant-human-vegf165-protein-bk2010","title":"Recombinant Human VEGF165 protein - BK2010","description":"\u003cp\u003eRecombinant Human VEGF165 protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2010-10, BK2010-50, BK2010-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882158788787,"sku":"BK2010-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882158821555,"sku":"BK2010-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882158854323,"sku":"BK2010-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_04282a51-02ce-4607-8794-289e2f87450a.jpg?v=1702045100"},{"product_id":"recombinant-human-il-17a-protein-bk2011","title":"Recombinant Human IL-17A protein - BK2011","description":"\u003cp\u003eRecombinant Human IL-17A protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2011-10, BK2011-50, BK2011-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882158887091,"sku":"BK2011-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882158919859,"sku":"BK2011-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882158952627,"sku":"BK2011-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_021d2b53-dcb9-4f03-b5a8-69aad0bd03ab.jpg?v=1702045102"},{"product_id":"recombinant-human-il-5-protein-bk2012","title":"Recombinant Human IL-5 protein - BK2012","description":"\u003cp\u003eRecombinant Human IL-5 protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2012-10, BK2012-50, BK2012-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882159018163,"sku":"BK2012-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882159050931,"sku":"BK2012-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882159083699,"sku":"BK2012-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_29d7ae48-65d3-48c0-a879-2822cd7b7f10.jpg?v=1702045105"},{"product_id":"recombinant-human-il-10-protein-bk2013","title":"Recombinant Human IL-10 protein - BK2013","description":"\u003cp\u003eRecombinant Human IL-10 protein\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK2013-10, BK2013-50, BK2013-100\u003c\/p\u003e\n\n\u003cp\u003eSizes:10μg, 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882159116467,"sku":"BK2013-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882159149235,"sku":"BK2013-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882159182003,"sku":"BK2013-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4a3f1494-6327-4254-b24c-dfc77f1ba331.jpg?v=1702045107"},{"product_id":"recombinant-human-growth-differentiation-factor-15gdf15-protein-bk2023","title":"Recombinant Human Growth differentiation factor 15(GDF15) protein - BK2023","description":"\u003cp\u003eRecombinant Human Growth differentiation factor 15(GDF15) protein\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: BK2023-10, BK2023-50, BK2023-100\u003c\/p\u003e\n\u003cp\u003eSizes: 10μg, 50μg, 100μg\u003c\/p\u003e\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882159214771,"sku":"BK2023-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882159247539,"sku":"BK2023-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882159280307,"sku":"BK2023-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5ff5ff67-2082-4bd9-bcdf-cf17e1b66a71.jpg?v=1702045109"},{"product_id":"recombinant-mouse-il-6-protein-bk2024","title":"Recombinant Mouse IL-6 protein - BK2024","description":"\u003cp\u003eRecombinant Mouse IL-6 protein\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: BK2024-10, BK2024-50, BK2024-100\u003c\/p\u003e\n\u003cp\u003eSizes: 10μg, 50μg, 100μg\u003c\/p\u003e\n\u003cp\u003eSource: E.coli\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882159313075,"sku":"BK2024-10","price":174.12,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42882159345843,"sku":"BK2024-50","price":550.59,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42882159378611,"sku":"BK2024-100","price":785.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_71345bb4-5693-449d-83ee-3a9b4e6c88a8.jpg?v=1702045111"},{"product_id":"recombinant-glutathione-s-transferase-bk0064","title":"Recombinant Glutathione S-Transferase - BK0064","description":"\u003cp\u003eRecombinant Glutathione S-Transferase\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0064-1000, BK0066-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 1mg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 26.98kD\u003c\/p\u003e\n\n\u003cp\u003ePurity: This product is chromatographically purified and predominantly shows a single band during SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity:\u003c\/p\u003e \n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation:\u003c\/p\u003e \n\n\u003cp\u003eAA Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK\u003cbr\u003e\n WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN\u003cbr\u003e\n MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV\u003cbr\u003e\n DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD\u003cbr\u003e\n VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA\u003cbr\u003e\n WPLQGWQATF GGGDHPPKSD LVPRGSPGIH RD\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin:\u003c\/p\u003e \n\n\u003cp\u003eReconstitution: Add 1 ml of dH2O to make the final concentration of 1 mg\/ml in 1X PBS\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product is lyophilized in 1X PBS, and it remains stable for several weeks if stored at 4°C. It may be stored it at -20°C for longer periods.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Glutathione S-Transferase (GST), an antioxidant enzyme, is involved in the primary cellular defense mechanism against reactive oxygen species. GST is soluble in water and has a mass of 26.98 kDa. It occurs as a dimer in all aerobic organisms.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"1mg","offer_id":42882239758515,"sku":"BK0064-1000","price":494.12,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_76338812-9005-4efd-8f60-9e00773e91f6.jpg?v=1702049841"},{"product_id":"recombinant-streptavidin-bk0163","title":"Recombinant Streptavidin - BK0163","description":"Recombinant Streptavidin\n\nCatalogue Numbers: BK0163-5mg, BK0165-1000\n\nSizes: 5mg, 1000IU\n\nSource: Escherichia coli\n\nMolecular Weight: 13,500 Da\n\nPurity: This product is affinity purified by 2-IminoBiotin Resin (GenScrtipt，Cat. No. L00272) with the purity more than 95% and shows predominantly a single band by SDS-PAGE.\n\nBiological Activity: \u0026gt;15 U\/mg protein, 1 U is defined as the quantity of protein that binds 1 microgramme\n\nPhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\n\nFormulation: \n\nAA Sequence: 0\n\nEndotoxin: \n\nReconstitution: \n\nStorage: The powder may be stored at 4°C for several weeks. For long-term storage, store at -20°C.\n\nUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\n\nDescription: Streptavidin is a biotin-binding protein found in the culture broth of the bacterium Streptomyces avidinii. Streptavidin can bind to four moles of biotin per mole of protein,and it shows extremely high affinity, approximately 10,000-15,000 Da. Streptavidin lacks the carbohydrate side chains present on avidin and has an isoelectric point of 6.5 to avidin's 10 far closer to that at which most useful biological interactions occur. As a result, Streptavidin frequently exhibits much lower non-specific binding than avidin does.","brand":"BioWorld","offers":[{"title":"5mg","offer_id":42882246803635,"sku":"BK0163-5mg","price":823.53,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0c63002f-a90e-4425-be5f-d3ddd3560864.jpg?v=1702050007"},{"product_id":"recombinant-tev-protease-his-bk0165","title":"Recombinant TEV Protease, His - BK0165","description":"\u003cp\u003eRecombinant TEV Protease, His\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0165-1000, BK0168-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 1000IU, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 28.4 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: 6 IU\/μl. Unit Definition: One unit of TEV protease cleaves \u0026gt; 85% of 3 μg of control substrate in 1 hour at pH 8.0 at 30°C.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Sterile liquid solution contains 50mM Tris, 5mM DTT, 50% glycerol, pH7.5.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: 0\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin:\u003c\/p\u003e \n\n\u003cp\u003eReconstitution:\u003c\/p\u003e \n\n\u003cp\u003eStorage: Recombinant Tobacco Etch Virus Protease (rTEV) remains stable up to 1 year at -20°C from date of receipt. Please avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Tobacco Etch Virus Protease is a highly site-specific cysteine protease that is found in the Tobacco Etch Virus (TEV). The optimum recognition site for this enzyme is the sequence Glu-Asn-Leu-Tyr-Phe-Gln-(Gly\/Ser) [ENLYFQ(G\/S)] and cleavage occurs between the Gln and Gly\/Ser residues, The most commonly used sequence is ENLYFQG. The protease is used to cleave affinity tags from fusion proteins. The optimal temperature for cleavage is 30°C; also it can be used at temperature as low as 4°C. It is recommended that the cleavage for each fusion protein be optimized by varying the amount of recombinant viral TEV protease, reaction time, or incubation temperature. It can be removed by Ni2+ affinity resin.Recombinant Tobacco Etch Virus Protease (rTEV) contains 231 amino acids with N-terminal His tagged. A fully biologically active molecule, rTEV has a molecular mass of 28.4 kDa and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"1000IU","offer_id":42882246869171,"sku":"BK0165-1000","price":317.65,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d157edeb-cd1d-46aa-a262-f49832977413.jpg?v=1702050009"},{"product_id":"recombinant-tnf-α-his-mouse-bk0170","title":"Recombinant TNF-α, His, Mouse - BK0170","description":"\u003cp\u003eRecombinant TNF-α, His, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0170-100, BK0171-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 18.3kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50\u0026lt;0.05ng\/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of \u0026gt; 2x 10ˆ7units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MHHHHHHML RSSSQNSSDK PVAHVVANHQ VEEQLEWLSQ RANALLANGM DLKDNQLVVP ADGLYLVYSQ VLFKGQGCPD YVLLTHt VSR FAISYQEKVN LLSAVKSPCP KDTPEGAELK PWYEPIYLGG VFQLEKGDQL SAEVNLPKYL DFAESGQVYF GVIAL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt;1 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant mouse Tumor Necrosis Factor-alpha (rmTNF-slpha) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rmTNF-alpha should be stable up to 4 week at 4°C or up to 6 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Tumor Necrosis Factor-Alpha (TNF-alpha) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.Recombinant mouse Tumor Necrosis Factor-alpha (rmTNF-alpha) produced in E. coli is a non-glycosylated polypeptide chain of 163 amino acids. A fully biologically active molecule, rhTNF-alpha has a molecular mass of 18.3kDa analyzed by reducing SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100μg","offer_id":42882247131315,"sku":"BK0170-100","price":823.53,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_eb0d540e-5894-47b7-9fcf-1ca2ea788115.jpg?v=1702050015"},{"product_id":"recombinant-tnf-α-human-bk0171","title":"Recombinant TNF-α, Human - BK0171","description":"\u003cp\u003eRecombinant TNF-α, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0171-10, BK0173-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 17.3 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98% as analyzed by SDS-PAGE and HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 30 pg\/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of \u0026gt; 3.3 x 10ˆ7 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: VRS SSRTPSDKPV AHVVANPQAE GQLQWLNRRA NALLANGVEL RDNQLVVPSE GLYLIYSQVL FKGQGCPSTH VLLTHTISRI AVSYQTKVNL LSAIKSPCQR ETPEGAEAKP WYEPIYLGGV FQLEKGDRLS AEINRPDYLD FAESGQVYFG IIAL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.2 EU\/μg determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Human Tumor Necrosis Factor-alpha (TNF-α), remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human TNF-α should be stable up to 1 week at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha(TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease.Recombinant Human Tumor Necrosis Factor-alpha (TNF-α) produced in E.coli is a single non-glycosylated polypeptide chain containing 157 amino acids. A fully biologically active molecule, rhTNF-α has a molecular mass of 17.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882247164083,"sku":"BK0171-10","price":155.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_79a268e7-59ca-43d5-abe4-3dcad408fb1c.jpg?v=1702050017"},{"product_id":"recombinant-il-7-his-human-cho-expre-ssed-bk0255","title":"Recombinant IL-7, His, Human (CHO-expressed) - BK0255","description":"\u003cp\u003eRecombinant IL-7, His, Human (CHO-expre Ssed)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0255-25, BK0256-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 24-34 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt;0.2ng \/ml, measured in a cell proliferation assay using 2E8 cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: DCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLL\u003cbr\u003e\n KVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEHHHHHHH\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Interleukin-7 (IL-7), His remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human Interleukin-7 (IL-7), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin-7 (IL-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7\/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 binds and signals through IL-7 receptor, a heterodimer consisting of IL-7 receptor alpha and common gamma chain receptor. IL-7 plays a role in regulating early B cell and T cell development. It is also important for optimal dendritic cell-T cell interaction.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"25μg","offer_id":42882257223859,"sku":"BK0255-25","price":494.12,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f50d6af4-1f4a-4b82-b805-4ac9420fdd76.jpg?v=1702050167"},{"product_id":"recombinant-enterokinase-lightchain-porcine-bk0339","title":"Recombinant Enterokinase, LightChain, Porcine - BK0339","description":"\u003cp\u003eRecombinant Enterokinase, LightChain, Porcine\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0339-100, BK0339-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100IU, 100IU\u003c\/p\u003e\n\n\u003cp\u003eSource: P. pastoris\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Theoretical MW: 21,880 DaThe apparent MW on SDS-PAGE: about 40,000 Da\u003c\/p\u003e\n\n\u003cp\u003ePurity:\u003c\/p\u003e \n\n\u003cp\u003eBiological Activity: One unit is defined as the amount of enzyme needed to cleave 50 μg of fusion protein in 16 hours to 95% completion at 22°C in a buffer containing 25 mM Tris-HCl, pH 8.0.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: GenScript enterokinase, formulated using GenScript's proprietary technology, can be shipped at room temperature. It will remain stable at 37°C for one week without losing any activity.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: 0\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin:\u003c\/p\u003e \n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20°C after delivery.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: GenScript Enterokinase is a highly purified recombinant porcine enterokinase. The enzyme has been extensively purified and tested to ensure that there are no other contaminating proteases. Enterokinase is a specific protease that cleaves after a lysine preceded by four aspartic acids: Asp-Asp-Asp-Asp-Lys. Enterokinase will not cleave, however, if this lysine is followed by a proline. Enterokinase can remove fusion tags is located in the N-terminal section of proteins, useful for removing unwanted tags.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100IU","offer_id":42882264891571,"sku":"BK0339-100","price":268.24,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fe3ac022-9589-460a-ac99-8c93320fdefc.jpg?v=1702050345"},{"product_id":"recombinant-enterokinase-porcine-bk0339","title":"Recombinant Enterokinase, Porcine - BK0339","description":"\u003cp\u003eRecombinant Enterokinase, Porcine\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0339-100, BK0341-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100IU, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: P. pastoris\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Theoretical MW: 21,880 Da; The apparent MW on SDS-PAGE: about 40,000 Da.\u003c\/p\u003e\n\n\u003cp\u003ePurity:\u003c\/p\u003e \n\n\u003cp\u003eBiological Activity: One unit is defined as the amount of enzyme needed to cleave 50 ug of fusion protein in 16 hours to 95% completion at 22°C in a buffer containing 25 mM Tris-HCl, pH 8.0.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: GenScript rPorcine Enterokinase, Lyophilized has been formulated using a proprietary technology, and the enzyme can be shipped at room temperature or stand at 37°C for 7 days without losing any activity.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: 0\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin:\u003c\/p\u003e \n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20°C after receiving. Reconstituted EK is stable for 24 hours at 2°C - 8°C. For long term storage, store it at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Enterokinase (EK) is a specific protease that cleaves a protein after lysine residue at its recognition site: Asp-Asp-Asp-Asp-Lys. Enterokinase will not work if the recognition site is followed by proline. If a fusion tag is placed at the N-terminus with an enterokinase site, enterokinase will be able to remove the fusion tag and to generate the protein exactly as you need without adding any unwanted residues. GenScript's Porcine Enterokinase is a highly purified recombinant porcine enterokinase (Light Chain) expressed from P. Pastoris GS115 and is supplied in two forms for customers: a. Liquid in 50% glycerol; b. Lyophilized (glycerol free).\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100IU","offer_id":42882264924339,"sku":"BK0339-100","price":268.24,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_939f8737-92f9-4f4a-b404-5e6bd87baddb.jpg?v=1702050347"},{"product_id":"recombinant-pdgf-bb-human-p-pastoris-expre-ssed-bk0343","title":"Recombinant PDGF-BB, Human (P. pastoris-expressed) - BK0343","description":"\u003cp\u003eRecombinant PDGF-BB, Human (P.pastoris-expre Ssed)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0343-10, BK0344-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: P. pastoris\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 24.3kDa, observed by non-reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt;3 ng\/ml, measured by the dose-dependent stimulation of the proliferation of Balb\/c 3T3 cells, corresponding to a specific activity of \u0026gt;3.3 x 10ˆ5 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 10mM acetic acid.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SL GSLTIAEPAM IAECKTRTEV FEISRRLIDR TNANFLVWPP CVEVQRCSGC CNNRNVQCRP TQVQLRPVQV RKIEIVRKKP IFKKAt VTLE DHLACKCEt V AAARPVT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt;1.0 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhPDGF-BB should be stable up to 4 weeks at 4°C or up to 6 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer.Recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) produced in Pichia pastoris is a glycosylated polypeptide. rhPDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids) and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882265252019,"sku":"BK0343-10","price":268.24,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_53c2154b-c5e6-4d02-a3ae-a7f14f0bfdf8.jpg?v=1702050354"},{"product_id":"recombinant-human-interleukin-1-alpha-rhuil-1α-pr1053","title":"Recombinant Human Interleukin-1 alpha (rHuIL-1α) - PR1053","description":"\u003cp\u003eRecombinant Human Interleukin-1 alpha (rHuIL-1α)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1053-2, PR1053-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 18.0 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of murine D10S cells is less then 0.001 ng\/ml, corresponding to a Specific Activity of ＞1 x 109 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKIt V ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-1α as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882215936179,"sku":"PR1053-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882215968947,"sku":"PR1053-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3ed28e0c-b6a9-470e-a65b-0a091ee8c32a.jpg?v=1702049457"},{"product_id":"recombinant-human-interleukin-1-beta-rhu-il-1β-pr1055","title":"Recombinant Human Interleukin-1 beta (rHu IL-1β) - PR1055","description":"\u003cp\u003eRecombinant Human Interleukin-1 beta (rHu IL-1β)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1055-2, PR1055-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 17.3 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of murine D10S cells is less than 1.0 pg\/ml, corresponding to a Specific Activity of ＞1.0 x 109 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIP\u003cbr\u003e\n VAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQ\u003cbr\u003e\n FPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-1β as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882216001715,"sku":"PR1055-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882216034483,"sku":"PR1055-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bbd3e752-9b87-46c1-b55f-b50045522470.jpg?v=1702049459"},{"product_id":"recombinant-human-interleukin-10-rhuil-10-pr1057","title":"Recombinant Human Interleukin-10 (rHuIL-10) - PR1057","description":"\u003cp\u003eRecombinant Human Interleukin-10 (rHuIL-10)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1057-2, PR1057-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 18.6kDa, a single non-glycosylated polypeptide chain containing 161 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Determined by the dose-dependent co-stimulation (with murine IL-4) of MC\/9 cells. The ED50 was found to be ≤ 2 ng\/ml, corresponding to a specific activity of ≥ 5 x 105 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLKESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-10 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin 10, also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 family of α-helical cytokines that also includes IL-19, IL-20, IL-22, IL-24, and IL-26\/AK155 . IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells . IL-10 is a 178 amino acid molecule that contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently associated homodimer . The IL-10 dimer binds to two IL-10 Rα\/IL-10R1 chains, resulting in recruitment of two IL-10 Rβ\/IL-10R2 chains and activation of a signaling cascade involving JAK1, TYK2, and STAT3 . IL-10Rβ does not bind IL-10 by itself but is required for signal transduction . IL-10 is a critical molecule in the control of viral infections and allergic and autoimmune inflammation . It promotes phagocytic uptake and Th2 responses but suppresses antigen presentation and Th1 proinflammatory responses.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882216067251,"sku":"PR1057-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882216100019,"sku":"PR1057-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_07636c25-75fc-4d78-9b19-0e9985fb5851.jpg?v=1702049460"},{"product_id":"recombinant-human-interleukin-11-rhuil-11-pr1058","title":"Recombinant Human Interleukin-11 (rHuIL-11) - PR1058","description":"\u003cp\u003eRecombinant Human Interleukin-11 (rHuIL-11)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1058-2, PR1058-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 19.1 kDa, a single non-glycosylated polypeptide chain containing 178 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of the proliferation of murine B9-11 was found to be less than 1 ng\/ml, corresponding to a specific activity of ＞1 x 107 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: PGPPPGPPR VSPDPRAELD St VLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-11 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin 11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive murine plasmacytoma cell line T1165. IL-11 was also independently discovered as an adipogenesis inhibitory factor (AGIF). The human IL-11 cDNA encodes a 199 amino acid residue precursor polypeptide with a 21 amino acid residue hydrophobic signal that is processed proteolytically to generate the 178 amino acid residue mature protein. IL-11 contains no cysteine residues or potential glycosylation sites.IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882216132787,"sku":"PR1058-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882216165555,"sku":"PR1058-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_be4d1112-ca86-4574-ad69-80a4b1a7ba94.jpg?v=1702049462"},{"product_id":"recombinant-human-interleukin-12-rhuil-12-pr1059","title":"Recombinant Human Interleukin-12 (rHuIL-12) - PR1059","description":"\u003cp\u003eRecombinant Human Interleukin-12 (rHuIL-12)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1059-2, PR1059-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 75 kDa, consisting of a 306 amino acid residue p40 subunit and a 197 amino acid residue p35 subunit.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. The ED50 for this effect is 0.1-0.2 ng\/mL, corresponding to a Specific Activity of ＞5 x 106 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSt V EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSEt VPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS p40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSAt VICRK NASISVRAQD RYYSSSWSEW ASVPCS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-12 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has been shown to have extensive amino acid sequence homology to the extracellular domain of the human IL-6 receptor while the p35 subunit shows distant but significant sequence similarity to IL-6, G-CSF, and chicken MGF. These observations have led to the suggestion that IL-12 might have evolved from a cytokine\/soluble receptor complex. Human and murine IL-12 share 70% and 60% amino acid sequence homology in their p40 and p35 subunits, respectively. IL-12 apparently shows species specificity with human IL-12 reportedly showing minimal activity in the murine system.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882216231091,"sku":"PR1059-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882216263859,"sku":"PR1059-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_58dc3e08-1f7e-4a05-a137-3ec2c881212d.jpg?v=1702049463"},{"product_id":"recombinant-human-interleukin-13-rhuil-13-pr1060","title":"Recombinant Human Interleukin-13 (rHuIL-13) - PR1060","description":"\u003cp\u003eRecombinant Human Interleukin-13 (rHuIL-13)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1060-2, PR1060-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately12.5 kDa, a single non-glycosylated polypeptide chain containing 114 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent proliferation of TF-1 cells was \u0026lt; 1.0 ng\/ml, corresponding to a specific activity of \u0026gt; 1 x 106 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SPGPVPPSTA LRELIEELVN ITQNQKAPLC NGSMVWSINL TAGMYCAALE SLINVSGCSA IEKTQRMLSG FCPHKVSAGQ FSSLHVRDTK IEVAQFVKDL LLHLKKLFRE GRFN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-13 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882218819763,"sku":"PR1060-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882218852531,"sku":"PR1060-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d9677ac5-598c-425e-9364-2a1a9e698750.jpg?v=1702049465"},{"product_id":"recombinant-human-interleukin-13-variant-rhuil-13-variant-pr1061","title":"Recombinant Human Interleukin-13 Variant (rHuIL-13 variant) - PR1061","description":"\u003cp\u003eRecombinant Human Interleukin-13 Variant (rHuIL-13 variant)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1061-2, PR1061-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 12.5 kDa, a single non-glycosylated polypeptide chain containing 114 amino acids, with a substitution of Q for R at position 112 compared with the wild type IL-13.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent proliferation of TF-1 cells was \u0026lt; 1.0 ng\/ml, corresponding to a specific activity of \u0026gt; 1×106 units\/mg. This analog has also been shown to exhibit increased in vivo activity compared to wild type IL-13.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.2, containing 5% trehalose.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SPGPVPPSTA LRELIEELVN ITQNQKAPLC NGSMVWSINL TAGMYCAALE\u003cbr\u003e\n SLINVSGCSA IEKTQRMLSG FCPHKVSAGQ FSSLHVRDTK IEVAQFVKDL\u003cbr\u003e\n LLHLKKLFRE GQFN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-13 variant as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: The human IL-13 cDNA encodes a 132 amino acid protein containing a proposed 20 amino acid signal peptide. Human IL-13 shares approximately 30% amino acid sequence homology to human IL-4 and the two cytokines exhibit overlapping biological activities. Human IL-13 is produced by activated Th0, Th1-like Th2-like and CD8 T cells. Similarly to IL-4, IL-13 has multiple effects on the differentiation and functions of monocytes\/macrophages. IL-13 can suppress the cytotoxic functions of monocytes\/macrophages. It can also suppress the production of proinflammatory cytokines and upregulate the production of IL-1ra by monocytes\/macrophages.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882218885299,"sku":"PR1061-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882218918067,"sku":"PR1061-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5f9d322d-4127-403b-b4c2-379b5510d8b4.jpg?v=1702049467"},{"product_id":"recombinant-human-interleukin-15-rhuil-15-pr1062","title":"Recombinant Human Interleukin-15 (rHuIL-15) - PR1062","description":"\u003cp\u003eRecombinant Human Interleukin-15 (rHuIL-15)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1062-2, PR1062-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 12.9 kDa, a single non-glycosylated polypeptide chain containing 115 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be \u0026lt; 0.5 ng\/ml., corresponding to a specific activity of \u0026gt; 2 x 106 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDt VENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-15 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin 15 is a recently identified novel cytokine that shares many biological properties with IL-2, including T, B and NK cell-stimulatory activities. cDNA clones encoding this cytokine have been isolated from simian, murine and human cell sources. Human IL-15 shares approximately 97% and 73% sequence identity with simian and murine IL-15, respectively. Both human and simian IL-15 are active on murine cells. Human IL-15 cDNA encodes a 162 amino acid residue precursor protein containing a 48 amino acid residue signal peptide that is cleaved to yield the 114 amino acid residue mature protein. The IL-15 mRNA is expressed by a wide variety of cells and tissues and is most abundantly expressed by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells. However, in activated peripheral blood T lymphocytes where IL-2 is highly expressed, the expression of IL-15 is not detectable. Although IL-15 lacks sequence homology with IL-2, it has recently been shown that both the beta and gamma chains of the IL-2 receptor are utilized for IL-15 binding and signaling. In addition, an IL-15 specific binding protein has also been cloned from a mouse T cell clone. (Grabstein, K. et al., 1994, Science 264:965; Giri, J. et al., 1994, EMBO J. 13:2822).\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882218950835,"sku":"PR1062-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882218983603,"sku":"PR1062-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_03e8d509-9c50-4851-b5bd-1d5584830cc2.jpg?v=1702049469"},{"product_id":"recombinant-human-interleukin-20-rhuil-20-pr1066","title":"Recombinant Human Interleukin-20 (rHuIL-20) - PR1066","description":"\u003cp\u003eRecombinant Human Interleukin-20 (rHuIL-20)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1066-2, PR1066-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 17.6 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Measured by its ability to activate STAT following receptor ligand interaction, it’s fully biologically active when compared to standard.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD\u003cbr\u003e\n TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL\u003cbr\u003e\n RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-20 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219016371,"sku":"PR1066-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219049139,"sku":"PR1066-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_08713b2e-4ece-493f-9d94-1d859d5a00f4.jpg?v=1702049471"},{"product_id":"recombinant-human-interleukin-21-rhuil-21-pr1067","title":"Recombinant Human Interleukin-21 (rHuIL-21) - PR1067","description":"\u003cp\u003eRecombinant Human Interleukin-21 (rHuIL-21)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1067-2, PR1067-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 15.4 kDa, a single non-glycosylated polypeptide chain containing 132 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Determined by its ability to proliferate activated B cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSAN\u003cbr\u003e\n TG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIH\u003cbr\u003e\n Q HLSSRTHGSE DS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-21 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells, stimulation (in conjuction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain (γc) found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21\/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219114675,"sku":"PR1067-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219147443,"sku":"PR1067-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_61fee0da-456f-49d3-8056-461c37452c00.jpg?v=1702049473"},{"product_id":"recombinant-human-interleukin-22-rhu-il-22-pr1068","title":"Recombinant Human Interleukin-22 (rHu IL-22) - PR1068","description":"\u003cp\u003eRecombinant Human Interleukin-22 (rHu IL-22)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1068-2, PR1068-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 33.6 kDa,non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Determined by its ability to activate STAT following receptor ligand interaction.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 5.0.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDt V KKLGESGEIK AIGELDLLFM SLRNACI\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-22 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β\/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219180211,"sku":"PR1068-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219212979,"sku":"PR1068-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5a504598-d06f-48d9-8371-c6f7d48e0309.jpg?v=1702049475"},{"product_id":"recombinant-human-interleukin-3-rhuil-3-pr1069","title":"Recombinant Human Interleukin-3 (rHuIL-3) - PR1069","description":"\u003cp\u003eRecombinant Human Interleukin-3 (rHuIL-3)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1069-2, PR1069-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 15 kDa, a single non-glycosylated polypeptide chain containing 133 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells is less than 0.1 ng\/ml, corresponding to a Specific Activity of ＞1.0 x 107 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-3 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages. Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, burst promoting activity, multicolony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. In addition to activated T cells, other cell types such as human thymic epithelial cells, activated murine mast cells, murine keratinocytes and neurons\/astrocytes can also produce IL-3. At the amino acid sequence level, mature human and murine IL-3 share only 29% sequence identity. Consistent with this lack of homology, IL-3 activity is highly species-specific and human IL-3 does not show activity on murine cells.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219245747,"sku":"PR1069-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219278515,"sku":"PR1069-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c5580385-921f-4668-bd0f-69971c707bf3.jpg?v=1702049477"},{"product_id":"recombinant-human-interleukin-31-rhu-il-31-pr1070","title":"Recombinant Human Interleukin-31 (rHu IL-31) - PR1070","description":"\u003cp\u003eRecombinant Human Interleukin-31 (rHu IL-31)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1070-2, PR1070-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 15.8 kDa, a single non-glycosylated polypeptide chain containing 141 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard.Measured by its ability to induce STAT3 activation in U-87 MG human glioblastoma\/astrocytoma cells. 5 ng\/mL of rhIL31 can effectively induce STAT3 activation.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-31 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL\/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219311283,"sku":"PR1070-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219344051,"sku":"PR1070-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_99bfb679-4eee-4e16-8579-a21d3b1e8743.jpg?v=1702049479"},{"product_id":"recombinant-human-interleukin-33-rhuil-33-pr1071","title":"Recombinant Human Interleukin-33 (rHuIL-33) - PR1071","description":"\u003cp\u003eRecombinant Human Interleukin-33 (rHuIL-33)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1071-2, PR1071-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤0.05ng\/ml, corresponding to a specific activity of ≥2×107units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, 150mM NaCl, 1mM EDTA, 2mM β-Mercaptoethanol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVLLSYYESQHPS NE\u003cbr\u003e\n SGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEKPLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCTENILFKLSET\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-33 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL33, also known as NFHEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription. IL33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. IL-33 shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1\/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219442355,"sku":"PR1071-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219475123,"sku":"PR1071-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a2fe1a90-6bb4-4d12-afa4-6139f37f9ede.jpg?v=1702049481"},{"product_id":"recombinant-human-interleukin-7-rhuil-7-pr1074","title":"Recombinant Human Interleukin-7 (rHuIL-7) - PR1074","description":"\u003cp\u003eRecombinant Human Interleukin-7 (rHuIL-7)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1074-2, PR1074-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 17.4 kD, a single non-glycosylated polypeptide chain containing 153 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Test in process\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA\u003cbr\u003e\n NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR\u003cbr\u003e\n KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-7 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219507891,"sku":"PR1074-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219540659,"sku":"PR1074-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f2af0d88-df5c-4b85-8434-f0e00f8c1d55.jpg?v=1702049483"},{"product_id":"recombinant-human-keratinocye-growth-factor-1-rhukgf-1-pr1079","title":"Recombinant Human Keratinocye Growth Factor-1 (rHuKGF-1) - PR1079","description":"\u003cp\u003eRecombinant Human Keratinocye Growth Factor-1 (rHuKGF-1)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1079-2, PR1079-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 19.0 kDa, a single, non-glycosylated polypeptide chain containing 164 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: The biological activity was determined by the does-dependent stimulation of thymidine uptake by BaF3 cells expressing KGF receptors yielding an ED50 \u0026lt;10ng\/ml,corresponding to a specific activity of ≥ 1 x 105 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered solution in 20mM PB, pH 8.0, 1M NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MCNDMTPEQMATNVNCSSPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRt VAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuKGF-1 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Keratinocyte Growth Factor-1 (KGF-1\/FGF-7) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1\/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF-1\/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219606195,"sku":"PR1079-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219638963,"sku":"PR1079-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_506eba10-71dd-45c8-9b47-58e493b100d5.jpg?v=1702049486"},{"product_id":"recombinant-human-macrophage-colony-stimulating-factor-rhum-csf-pr1083","title":"Recombinant Human Macrophage Colony Stimulating Factor (rHuM-CSF) - PR1083","description":"\u003cp\u003eRecombinant Human Macrophage Colony Stimulating Factor (rHuM-CSF)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1083-2, PR1083-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Baculovirus infected Silkworm\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 42.0 kDa, a covalently linked homodimer, of two 21.0 kDa polypeptide monomers (1-149 amino acid of human M-CSF).\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of the proliferation of murine M-NSF-60 cells is less than 3.0 ng\/ml, corresponding to a Specific Activity of ＞3.3 x 105 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDKACVRTFYETP LQLLEKVKNV FNETKNLLDK DWNIFSKNCN NSFAECSSQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuM-CSF as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water to a concentration of 0.1 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: M-CSF, also known as CSF-1, is a four α helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219671731,"sku":"PR1083-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219704499,"sku":"PR1083-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1592ce58-e525-43b9-bd5b-33c309d5bcb5.jpg?v=1702049488"},{"product_id":"recombinant-human-mcp-2-rhu-mcp-2-ccl8-pr1087","title":"Recombinant Human MCP-2 （rHu MCP-2\/CCL8） - PR1087","description":"\u003cp\u003eRecombinant Human MCP-2 （rHu MCP-2\/CCL8）\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1087-2, PR1087-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 8.9 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells.The ED50 for this effect is typically 0.03-0.1μg\/mL, corresponding to a Specific Activity of ＞1 x 104 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: QPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuMCP-2\/CCL8 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: MCP-2 and MCP-3 are two monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and MCP-3 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1.MCP-3 also shares 58% amino acid identity with MCP-2.\u003cbr\u003e\n Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition,the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219737267,"sku":"PR1087-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219770035,"sku":"PR1087-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4405a90d-aa46-45b2-b95a-037387b4cf71.jpg?v=1702049490"},{"product_id":"recombinant-human-mip-1-beta-rhu-mip-1-beta-ccl4-pr1095","title":"Recombinant Human MIP-1 beta (rHu MIP-1 beta \/CCL4) - PR1095","description":"\u003cp\u003eRecombinant Human MIP-1 beta (rHu MIP-1 beta \/CCL4)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1095-2, PR1095-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 7.6 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;96% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 5.0-20.0 ng\/ml, corresponding to a Specific Activity of ＞5 x 104 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM Tris, 500mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESW\u003cbr\u003e\n VQ EYVYDLELN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuMIP-1 beta \/CCL4 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219835571,"sku":"PR1095-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219868339,"sku":"PR1095-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_6d1b4168-c599-45b7-bc50-a0714d947026.jpg?v=1702049492"},{"product_id":"recombinant-human-mip-4-rhumip-4-ccl18-pr1098","title":"Recombinant Human MIP-4 (rHuMIP-4\/CCL18) - PR1098","description":"\u003cp\u003eRecombinant Human MIP-4 (rHuMIP-4\/CCL18)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1098-2, PR1098-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 7.8 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by its ability to chemoattract human T lymphocytes using a concentration range of 1.0 -10.0 ng\/ml, corresponding to a Specific Activity of ＞1 x 105 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: AQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuMIP-4\/CCL18 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: CCL18, is a novel CC chemokine that is highly homologous to MIP-1α (61% amino acid sequence identity). CCL18 cDNA encodes an 89 aa residue precursor protein with a 20 aa putative signal peptide that is cleaved to generate a 69 aa residue mature protein which lacks potential glycosylation sites. In vitro, CCL18 mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10 and IL-13, and inhibited by IFN-γ. CCL18 mRNA is also expressed by GM-CSF\/IL-4-induced monocyte-derived dendritic cells. In vivo, CCL18 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells. Recombinant CCL18 has been shown to chemoattract naive T cells, but not monocytes or neutrophils.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219901107,"sku":"PR1098-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219933875,"sku":"PR1098-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9ce7520d-8895-442f-aab9-35154d2e9a9e.jpg?v=1702049494"},{"product_id":"recombinant-human-monocyte-chemotactic-protein-3-ccl7-rhumcp-3-ccl7-pr1100","title":"Recombinant Human Monocyte Chemotactic Protein-3\/CCL7 (rHuMCP-3\/CCL7) - PR1100","description":"\u003cp\u003eRecombinant Human Monocyte Chemotactic Protein-3\/CCL7 (rHuMCP-3\/CCL7)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1100-2, PR1100-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng\/ml, corresponding to a Specific Activity of ＞1 x 104 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE\u003cbr\u003e\n ICADPTQKWV QDFMKHLDKK TQTPKL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuMCP-3\/CCL7 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2.\u003cbr\u003e\n Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882219966643,"sku":"PR1100-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882219999411,"sku":"PR1100-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b35eb937-4f7f-4c83-a878-fb5ed22e5e0d.jpg?v=1702049496"},{"product_id":"recombinant-human-nap-2-rhunap-2-cxcl7-pr1101","title":"Recombinant Human NAP-2 (rHuNAP-2\/CXCL7) - PR1101","description":"\u003cp\u003eRecombinant Human NAP-2 (rHuNAP-2\/CXCL7)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1101-2, PR1101-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 7.6 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by its ability to chemoattract human neutrophils using a concentration range of 1.0-10.0 ng\/ml, corresponding to a Specific Activity of ＞1 x 105 IU\/mg\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuNAP-2\/CXCL7 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and to chemoattract and activate neutrophils. Although CTAP-III, β-TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882220032179,"sku":"PR1101-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882220064947,"sku":"PR1101-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_666b5660-0188-4c22-b066-2e1a3023b07a.jpg?v=1702049498"},{"product_id":"recombinant-human-neurotrophin-4-rhunt-4-pr1102","title":"Recombinant Human Neurotrophin-4 (rHuNT-4 ) - PR1102","description":"\u003cp\u003eRecombinant Human Neurotrophin-4 (rHuNT-4 )\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1102-2, PR1102-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 28 kDa, a noncovalently linked homodimer of two 14.0 kDa polypeptide monomers (260 total amino acid residues).\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng\/ml, corresponding to a Specific Activity of ＞2 x 104 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: GVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACV CTLLSRTGRA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuNT-4 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Neurotrophin-4 (NT-4), also known as NT-5, is a member of the NGF family of neuronal and epithelial growth factors. Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. Human NT-4 shares 48 - 52% aa sequence identity with human beta-NGF, BDNF, and NT-3. It shares 91% and 95% aa sequence identity with mouse and rat NT-4\/5, respectively. The mature protein is secreted as a homodimer and can also form heterodimers with BDNF or NT-3. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 promotes the development and survival of selected peripheral and CNS neurons. NT-4 induced TrkB signaling augments NMDA receptor activity and increases neuronal sensitivity to excitotoxic cell death. It also promotes the proliferation of keratinocytes and accelerates hair follicle regression during the follicular cycle. NT-4 is secreted by activated T cells and granulocytes at sites of inflammation where it contributes to tissue regeneration.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882220097715,"sku":"PR1102-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882220130483,"sku":"PR1102-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a877e20c-cae5-460f-a599-0170287f042b.jpg?v=1702049500"},{"product_id":"recombinant-human-oncostatin-m-rhuosm-pr1104","title":"Recombinant Human Oncostatin-M (rHuOSM) - PR1104","description":"\u003cp\u003eRecombinant Human Oncostatin-M (rHuOSM)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1104-2, PR1104-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 26.0 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to the standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is \u0026lt; 2 ng\/ml, corresponding to a specific activity of \u0026gt; 5×105 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRKGKRLMTRGQLPR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-1α as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882220196019,"sku":"PR1104-2","price":185.88,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":42882220228787,"sku":"PR1104-10","price":350.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_8a289ef9-4192-425d-a7e5-b12a4474a242.jpg?v=1702049502"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/collections\/LOGO_Clipped_for_website_95180d0a-6a1a-4326-b1fc-cdb933a63baa.png?v=1701974264","url":"https:\/\/afsbio.com\/collections\/cytokines.oembed?page=3","provider":"AFSBio Inc.","version":"1.0","type":"link"}