OAS1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2530-20, A2530-100
Citations, Manuals and SDS Available upon request.
Background: This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12.
Synonyms: OIAS; IFI-4; OIASI; IMD100; E18/E16; OAS1
GeneID: 4938
Swiss-Prot: P00973
Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Calculated Molecular Weight: 46kDa
Observed Molecular Weight: 40kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_058132.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling
Recommended Dilutions: WB: 1:500 - 1:2000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Endoplasmic Reticulum, Microsome, Mitochondrion, Nucleus, Secreted
Positive Samples: Mouse liver
Keywords: 4938, (2 5)oligo(A) synthase 1, 2 5 oligoadenylate synthase 1, 2 5A synthase 1, E18/E16, IFI 4, OAS1, OIAS, OIASI, p46/p42 OAS, IFI-4, 2'-5'-oligoadenylate synthetase 1, 2'-5'-oligoadenylate synthase 1, (2-5')oligo(A) synthase 1, 2', 5'-oligo A synthetase 1, 40/46kDa, 2'-5'-oligoisoadenylate synthetase 1, 2-5A synthase 1, 2-5A synthetase 1, E16 (2'-5') oligo A synthetase, P00973, 2', -5', -Oligoadenylate Synthetase 1, 2-5-Oligoadenylate Synthetase 1, (2-5)Oligo(A) Synthase 1, 2-5A Synthase 1, 2, 5-Oligoadenylate Synthetase 1 (40-46 KD), 2-5-Oligoisoadenylate Synthetase 1, 2-5-Oligoadenylate Synthase 1, E16 (2-5) Oligo A Synthetase, 5-Oligo A Synthetase 1, 2-5A Synthetase 1, P46/P42 OAS, EC 2.7.7.84, IFI4, 免疫, 炎症, 天然免疫, 感染, 病毒, 自身免疫, Mavs
Symbol: OAS1
Category: Polyclonal Antibodies
Research Use Only