{"product_id":"α-actinin-rabbit-pab-ea230","title":"α-actinin Rabbit pAb - EA230","description":"\u003cp\u003eα-actinin Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EA230-50, EA230-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-2, 000 IHC 1:200-500\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 103kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 87\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P12814\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell junction,  Cell membrane,  Cell projection,  Cytoplasm,  Cytoskeleton,  Membrane\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201977409715,"sku":"EA230-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201977442483,"sku":"EA230-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a38bcf9b-bbb2-4dd1-88de-c1fabfce38f0.png?v=1767119207","url":"https:\/\/afsbio.com\/products\/%ce%b1-actinin-rabbit-pab-ea230","provider":"AFSBio Inc.","version":"1.0","type":"link"}