{"product_id":"14-3-3-beta-polyclonal-antibody-bt-ap00003","title":"14-3-3 Beta Polyclonal Antibody - BT-AP00003","description":"\u003cp\u003e14-3-3 Beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00003-20, BT-AP00003-50, BT-AP00003-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: YWHAB encodes a protein (tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein beta) belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for YWHAB.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: YWHAB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 14-3-3 beta Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 28082\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P31946; Mouse: Q9CQV8; Rat: P35213\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: YWHAB; 14-3-3 protein beta\/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7529; Mouse: 54401; Rat: 56011\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240078926003,"sku":"BT-AP00003-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240078958771,"sku":"BT-AP00003-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240078991539,"sku":"BT-AP00003-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d0732f50-ed19-465e-b7ad-b788c3886ae4.png?v=1769403120","url":"https:\/\/afsbio.com\/products\/14-3-3-beta-polyclonal-antibody-bt-ap00003","provider":"AFSBio Inc.","version":"1.0","type":"link"}