{"product_id":"14-3-3-beta-polyclonal-antibody-bt-ap00004","title":"14-3-3 Beta Polyclonal Antibody - BT-AP00004","description":"\u003cp\u003e14-3-3 Beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00004-20, BT-AP00004-50, BT-AP00004-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: YWHAZ (tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein zeta) product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5and#39; UTR but that encode the same protein have been identified for YWHAZ.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: YWHAZ\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 14-3-3 beta Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27745\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P63104\/P31946; Rat: P63102\/P35213\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: YWHAZ; 14-3-3 protein zeta\/delta; Protein kinase C inhibitor protein 1; KCIP-1; YWHAB; 14-3-3 protein beta\/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7534\/7529; Mouse: 22631\/54401; Rat: 25578\/56011\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240079024307,"sku":"BT-AP00004-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240079057075,"sku":"BT-AP00004-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240079089843,"sku":"BT-AP00004-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_acc8ac86-57e0-4367-879b-bcab23da1cd1.png?v=1769403121","url":"https:\/\/afsbio.com\/products\/14-3-3-beta-polyclonal-antibody-bt-ap00004","provider":"AFSBio Inc.","version":"1.0","type":"link"}