{"product_id":"14-3-3-theta-polyclonal-antibody-bt-ap00012","title":"14-3-3 Theta Polyclonal Antibody - BT-AP00012","description":"\u003cp\u003e14-3-3 Theta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00012-20, BT-AP00012-50, BT-AP00012-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein theta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: YWHAQ\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 14-3-3 theta Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27764\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P27348; Mouse: P68254; Rat: P68255\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: YWHAQ; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10971; Mouse: 22630; Rat: 25577\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240079810739,"sku":"BT-AP00012-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240079843507,"sku":"BT-AP00012-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240079876275,"sku":"BT-AP00012-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7eb0a6e7-dbb1-424a-a359-06b24fa4e118.png?v=1769403134","url":"https:\/\/afsbio.com\/products\/14-3-3-theta-polyclonal-antibody-bt-ap00012","provider":"AFSBio Inc.","version":"1.0","type":"link"}