{"product_id":"17beta-hsd4-polyclonal-antibody-bt-ap00017","title":"17Beta-HSD4 Polyclonal Antibody - BT-AP00017","description":"\u003cp\u003e17Beta-HSD4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00017-20, BT-AP00017-50, BT-AP00017-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peroxisomal multifunctional enzyme type 2 encoded by HSD17B4 is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HSD17B4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 17beta-HSD4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 79686\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P51659; Mouse: P51660; Rat: P97852\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HSD17B4; EDH17B4; Peroxisomal multifunctional enzyme type 2; MFE-2; 17-beta-hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; D-bifunctional protein; DBP; Multifunctional protein 2; MPF-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3295; Mouse: 15488; Rat: 79244\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240080203955,"sku":"BT-AP00017-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240080236723,"sku":"BT-AP00017-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240080269491,"sku":"BT-AP00017-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6801404e-ea5c-4353-8fd2-b37ce6ec7dac.png?v=1769403141","url":"https:\/\/afsbio.com\/products\/17beta-hsd4-polyclonal-antibody-bt-ap00017","provider":"AFSBio Inc.","version":"1.0","type":"link"}