{"product_id":"2-o-methylguanosine-gm-rabbit-pab-a20697","title":"2'-O-Methylguanosine (Gm) Rabbit pAb - A20697","description":"\u003cp\u003e2'-O-Methylguanosine (Gm) Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A20697-20, A20697-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm), 2'-O-methylcytidine (Cm), 2'-O-methyluridine (Um), N 6-methyladenosine (m6A), N 1-methylguanosine (m1G), 5-methylcytidine (m5C), and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Other Modified Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: DB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Species independent\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: Refer to figures\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Chemical compounds corresponding to 2'-O-Methylguanosine (Gm).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: DB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189368348851,"sku":"A20697-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189368381619,"sku":"A20697-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_1f73709f-6560-4739-b979-9f3c8606b2a8.png?v=1766425608","url":"https:\/\/afsbio.com\/products\/2-o-methylguanosine-gm-rabbit-pab-a20697","provider":"AFSBio Inc.","version":"1.0","type":"link"}