{"product_id":"3bp1-polyclonal-antibody-bt-ap08359","title":"3BP1 Polyclonal Antibody - BT-AP08359","description":"\u003cp\u003e3BP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08359-20, BT-AP08359-50, BT-AP08359-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene| SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.|sequence Translated as Cys.|Contains 1 BAR domain.|Contains 1 Rho-GAP domain.|\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SH3BP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SH3 domain-binding protein 1\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y3L3; Mouse: P55194\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SH3 domain-binding protein 1;3BP-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23616\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238980378803,"sku":"BT-AP08359-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238980411571,"sku":"BT-AP08359-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238980444339,"sku":"BT-AP08359-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_37158658-fafc-4170-a748-09181f9d1abd.png?v=1769387509","url":"https:\/\/afsbio.com\/products\/3bp1-polyclonal-antibody-bt-ap08359","provider":"AFSBio Inc.","version":"1.0","type":"link"}