{"product_id":"3bp2-polyclonal-antibody-bt-ap08360","title":"3BP2 Polyclonal Antibody - BT-AP08360","description":"\u003cp\u003e3BP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08360-20, BT-AP08360-50, BT-AP08360-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain| an SH3-binding proline-rich region| and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SH3BP2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SH3 domain-binding protein 2\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P78314; Mouse: Q06649\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SH3 domain-binding protein 2;3BP-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6452\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238980477107,"sku":"BT-AP08360-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238980509875,"sku":"BT-AP08360-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238980542643,"sku":"BT-AP08360-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8358398d-7056-46f9-8abb-ba5362dbbf82.png?v=1769387513","url":"https:\/\/afsbio.com\/products\/3bp2-polyclonal-antibody-bt-ap08360","provider":"AFSBio Inc.","version":"1.0","type":"link"}