{"product_id":"8-ohdg-dna-rna-damage-polyclonal-antibody-bs66180","title":"8-OHdG (DNA\/RNA Damage) Polyclonal Antibody - BS66180","description":"\u003cp\u003e8-OHdG (DNA\/RNA Damage) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66180-50, BS66180-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecμles that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: 8-hydroxy-2'-deoxyguanosine, 2'-Deoxy-8-oxoguanosine, 7, 8-Dihydro-8-oxo-2'-deoxyguanosine, 8-Oxo-7, 8-dihydro-2'-deoxyguanosine, 8-Oxo-7, 8-dihydrodeoxyguanosine, 2'-Deoxy-8-oxo-D-guanosine, 8-Oxo-7, 8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG, 2'-Deoxy-8-hydroxyguanosine\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated 8-OHdG\u003c\/p\u003e \n\n\u003cp\u003eDilution: ELISA=1:5000-10000 IHC=1:100-500 IF=1:100-500\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: 8-OHdG (DNA\/RNA Damage) polyclonal antibody detects endogenous levels of 8-OHdG protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 0.283 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936713531571,"sku":"BS66180-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936713564339,"sku":"BS66180-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/8-ohdg-dna-rna-damage-polyclonal-antibody-bs66180","provider":"AFSBio Inc.","version":"1.0","type":"link"}