{"product_id":"a-actinin-4a12-mouse-mab-em1261","title":"a-actinin (4A12) Mouse mAb - EM1261","description":"\u003cp\u003ea-actinin (4A12) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1261-50, EM1261-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 103kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 87\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P12814\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell junction,  Cell membrane,  Cell projection,  Cytoplasm,  Cytoskeleton,  Membrane\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201993269427,"sku":"EM1261-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201993302195,"sku":"EM1261-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_944fd94c-4963-4403-baed-dca843d721f9.png?v=1767119526","url":"https:\/\/afsbio.com\/products\/a-actinin-4a12-mouse-mab-em1261","provider":"AFSBio Inc.","version":"1.0","type":"link"}