{"product_id":"a-cyclase-v-vi-polyclonal-antibody-bt-ap00054","title":"A Cyclase V\/VI Polyclonal Antibody - BT-AP00054","description":"\u003cp\u003eA Cyclase V\/VI Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00054-20, BT-AP00054-50, BT-AP00054-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ADCY6\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: A Cyclase V\/VI Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 138908\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O95622\/O43306; Rat: Q04400\/Q03343\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase; ADCY5; Adenylate cyclase type 5; ATP pyrophosp\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 111\/112; Mouse: 224129\/11512; Rat: 64532\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240082202803,"sku":"BT-AP00054-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240082235571,"sku":"BT-AP00054-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240082268339,"sku":"BT-AP00054-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2993e86d-f868-41cd-bf08-18e3c53c60b6.png?v=1769403172","url":"https:\/\/afsbio.com\/products\/a-cyclase-v-vi-polyclonal-antibody-bt-ap00054","provider":"AFSBio Inc.","version":"1.0","type":"link"}