{"product_id":"abc3a-polyclonal-antibody-bt-ap05897","title":"ABC3A Polyclonal Antibody - BT-AP05897","description":"\u003cp\u003eABC3A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05897-20, BT-AP05897-50, BT-AP05897-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster| thought to result from gene duplication| on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity| by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines| which leads to DNA degradation. However| other mechanisms are also thought to be involved| as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: APOBEC3A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Probable DNA dC-\u0026gt;dU-editing enzyme APOBEC-3A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P31941\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Probable DNA dC-\u0026gt;dU-editing enzyme APOBEC-3A;EC 3.5.4.-;Phorbolin-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 100913187\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239035625651,"sku":"BT-AP05897-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239035658419,"sku":"BT-AP05897-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239035691187,"sku":"BT-AP05897-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ef58021d-2943-4e7b-b164-83d35cf70d85.png?v=1769388215","url":"https:\/\/afsbio.com\/products\/abc3a-polyclonal-antibody-bt-ap05897","provider":"AFSBio Inc.","version":"1.0","type":"link"}