{"product_id":"abca1-monoclonal-antibody-bt-mca3682","title":"ABCA1 Monoclonal Antibody - BT-MCA3682","description":"\u003cp\u003eABCA1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3682-50, BT-MCA3682-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6B7A11\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ABCA1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ABCA1 (AA: 2081-2261) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 254 kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O95477\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TGD, ABC1, CERP, ABC-1, HDLDT1, HPALP1, HDLCQTL13\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 19\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238389473459,"sku":"BT-MCA3682-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238389506227,"sku":"BT-MCA3682-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d5888a06-d22f-4a7c-9ff9-4bae8eaed89e.png?v=1769379770","url":"https:\/\/afsbio.com\/products\/abca1-monoclonal-antibody-bt-mca3682","provider":"AFSBio Inc.","version":"1.0","type":"link"}