{"product_id":"abca1-polyclonal-antibody-bt-ap13983","title":"ABCA1 Polyclonal Antibody - BT-AP13983","description":"\u003cp\u003eABCA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13983-20, BT-AP13983-50, BT-AP13983-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR\/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate| this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangierandapos;s disease and familial high-density lipoprotein deficiency.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ATP-binding cassette sub-family A member 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O95477; Mouse: P41233\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATP-binding cassette sub-family A member 1;ATP-binding cassette transporter 1;ABC-1;ATP-binding cassette 1;Cholesterol efflux regulatory protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 19\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239035920563,"sku":"BT-AP13983-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239035953331,"sku":"BT-AP13983-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239035986099,"sku":"BT-AP13983-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3d654c8e-fd25-46c7-8ff3-c82190101c79.png?v=1769388224","url":"https:\/\/afsbio.com\/products\/abca1-polyclonal-antibody-bt-ap13983","provider":"AFSBio Inc.","version":"1.0","type":"link"}