{"product_id":"abca1-polyclonal-antibody-e-ab-66766","title":"ABCA1 Polyclonal Antibody - E-AB-66766","description":"ABCA1 Polyclonal Antibody\n\nSizes: 60μL, 120μL, 200μL\n\nCatalogue Numbers: E-AB-66766-60, E-AB-66766-120, E-AB-66766-200\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: ABCA1\n\nTarget Synonym: ABCA1; ABC-1; ABC1; CERP; HDLDT1; TGD\n\nResearch Areas: Cancer,Cardiovascular,Metabolism,Neuroscience,Signal Transduction\n\nConjugation: Unconjugated\n\nHost: Rabbit\n\nSpecies Reactivity: Mouse\n\nApplication: IF\n\nIsotype: IgG\n\nClonality: Polyclonal\n\n \n\nUNIProt ID: O95477\n\nBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.\n\nConcentration: 1 mg\/mL\n\nImmunogen: Recombinant fusion protein of human ABCA1\n\nBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\n\nPurification Method: Affinity purification\n\nDilution: IF 1:50-1:200\n\nCalculated MW: 254kDa\n\nObserved MW: 270KDa\n\nStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\n\nShipping: Ice bag\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146427695283,"sku":"E-AB-66766-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146427728051,"sku":"E-AB-66766-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146427760819,"sku":"E-AB-66766-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1e3446a4-e842-468e-9f8a-266fd2bfc221.png?v=1710295389","url":"https:\/\/afsbio.com\/products\/abca1-polyclonal-antibody-e-ab-66766","provider":"AFSBio Inc.","version":"1.0","type":"link"}