{"product_id":"abca6-rabbit-polyclonal-antibody-es1561","title":"ABCA6 Rabbit Polyclonal Antibody - ES1561","description":"\u003cp\u003eABCA6 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1561-50, ES1561-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ABCA6, ATP-binding cassette sub-family A member 6\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from ABCA6. at AA range: 1180-1260\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ABCA6\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ABCA6 Polyclonal Antibody detects endogenous levels of ABCA6 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Widely expressed with higher expression in liver,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 185kD\u003c\/p\u003e\n\n\u003cp\u003eFields: ABC transporters\u003c\/p\u003e\n\n\u003cp\u003eFunction: Developmental Stage: Expressed in fetal kidney, lung and liver\u003cbr\u003e\nFunction: Probable transporter which may play a role in macrophage lipid homeostasis\u003cbr\u003e\nInduction: Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages\u003cbr\u003e\nSimilarity: Belongs to the ABC transporter family. ABCA subfamily\u003cbr\u003e\nSimilarity: Contains 2 ABC transporter domains\u003cbr\u003e\nTissue Specificity: Widely expressed with higher expression in liver\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Golgi apparatus membrane, Multi-pass membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ABCA6\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: ATP-binding cassette sub-family A member 6\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8K441\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315331485875,"sku":"ES1561-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315331518643,"sku":"ES1561-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/abca6-rabbit-polyclonal-antibody-es1561","provider":"AFSBio Inc.","version":"1.0","type":"link"}