{"product_id":"abcb11-polyclonal-antibody-e-ab-66326","title":"ABCB11 Polyclonal Antibody - E-AB-66326","description":"\u003cp\u003eABCB11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66326-60, E-AB-66326-120, E-AB-66326-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ABCB11\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ABCB11; ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Metabolism,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O95342\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR\/TAP subfamily. Members of the MDR\/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human ABCB11\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 146kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 146kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146413834419,"sku":"E-AB-66326-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146413867187,"sku":"E-AB-66326-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146413899955,"sku":"E-AB-66326-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_10b8fa66-2044-46ab-9a14-71eafffd7a27.png?v=1710295149","url":"https:\/\/afsbio.com\/products\/abcb11-polyclonal-antibody-e-ab-66326","provider":"AFSBio Inc.","version":"1.0","type":"link"}