{"product_id":"abcc13-polyclonal-antibody-bs62443","title":"ABCC13 Polyclonal Antibody-BS62443","description":"\u003cp\u003eABCC13 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62443-50, BS62443-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9NSE7\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB  IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000  IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The S-100 protein family consists of a group of calcium-binding proteins that are exclusively expressed in vertebrates and exhibit cell and tissue-specific expression. The expression levels of its members differ in various pathological conditions. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation and motility of tumor cells. S-100Z (S100 calcium-binding protein Z) is a 99 amino acid protein that shares 57% and 52% sequence identity with S-100A1 and S-100P, respectively. A dimeric, predominantly α-helical protein, S-100Z contains two EF-hand domains capable of binding calcium ions. Binding of calcium results in conformational changes and exposure of hydrophobic surfaces on the protein. S-100Z interacts with S-100P, and demonstrates highest level of expression in spleen and leukocytes. The S-100Z gene is conserved in chimpanzee, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q13.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ABCC13 polyclonal antibody detects endogenous levels of ABCC13 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ABCC13 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:HT29 whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 31 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ABCC13\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human ABCC13.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910458609843,"sku":"BS62443-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910458642611,"sku":"BS62443-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_93837c98-06c6-4b30-b630-c53e838357fb.jpg?v=1703092812","url":"https:\/\/afsbio.com\/products\/abcc13-polyclonal-antibody-bs62443","provider":"AFSBio Inc.","version":"1.0","type":"link"}