{"product_id":"abcg1-polyclonal-antibody-bs5596","title":"ABCG1 Polyclonal Antibody-BS5596","description":"\u003cp\u003eABCG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5596-50, BS5596-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P45844\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ABCG1 polyclonal antibody detects endogenous levels of ABCG1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 110 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ABCG1 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: Jurkat cell lysate\u003cbr\u003e\nLane 2: Mouse liver tissue lysate\u003cbr\u003e\nLane 3: Rat liver tissue lysate\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 633-678 of Human ABCG1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911808258227,"sku":"BS5596-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911808290995,"sku":"BS5596-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fff98392-5c3f-49e3-ac49-cd75a807f393.jpg?v=1703179674","url":"https:\/\/afsbio.com\/products\/abcg1-polyclonal-antibody-bs5596","provider":"AFSBio Inc.","version":"1.0","type":"link"}