{"product_id":"abcg2-monoclonal-antibody-bt-mca0123","title":"ABCG2 Monoclonal Antibody - BT-MCA0123","description":"\u003cp\u003eABCG2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0123-50, BT-MCA0123-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Signal transduction; Metabolism; Stem cells; Tags and; cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCG2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ICC, FCM, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ATP-binding cassette sub-family G member 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UNQ0; Mouse: Q7TMS5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD antigen CD338\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9429; Mouse: 26357\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238657482931,"sku":"BT-MCA0123-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238657515699,"sku":"BT-MCA0123-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2103aef6-09f7-44c9-832a-6a51d8fada07.png?v=1769383489","url":"https:\/\/afsbio.com\/products\/abcg2-monoclonal-antibody-bt-mca0123","provider":"AFSBio Inc.","version":"1.0","type":"link"}