{"product_id":"abcg2-monoclonal-antibody-bt-mca3431","title":"ABCG2 Monoclonal Antibody - BT-MCA3431","description":"\u003cp\u003eABCG2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3431-50, BT-MCA3431-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and cell markers, Signal transduction, Stem cells, Cancer, Metabolism\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: ABCG2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1H2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ABCG2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ABCG2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 72kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9UNQ0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, CDw338, EST157481, MGC102821\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 9429\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238598238387,"sku":"BT-MCA3431-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238598271155,"sku":"BT-MCA3431-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1ca27dbc-3117-4ca7-9b72-da059f0d5152.png?v=1769382930","url":"https:\/\/afsbio.com\/products\/abcg2-monoclonal-antibody-bt-mca3431","provider":"AFSBio Inc.","version":"1.0","type":"link"}