{"product_id":"abcg5-monoclonal-antibody-bt-mca4354","title":"ABCG5 Monoclonal Antibody - BT-MCA4354","description":"\u003cp\u003eABCG5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4354-50, BT-MCA4354-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal transduction, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCG5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1B5D8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ABCG5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 72.5kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9H222\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: STSL\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 64240\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238552199347,"sku":"BT-MCA4354-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238552232115,"sku":"BT-MCA4354-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4cfeb0b0-8bb4-4674-9a6d-63ab8535c975.png?v=1769382485","url":"https:\/\/afsbio.com\/products\/abcg5-monoclonal-antibody-bt-mca4354","provider":"AFSBio Inc.","version":"1.0","type":"link"}