{"product_id":"abcg5-polyclonal-antibody-bt-ap14037","title":"ABCG5 Polyclonal Antibody - BT-AP14037","description":"\u003cp\u003eABCG5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14037-20, BT-AP14037-50, BT-AP14037-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR\/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver| colon| and intestine. This gene is tandemly arrayed on chromosome 2| in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis| and have been observed in patients with sitosterolemia.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCG5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ATP-binding cassette sub-family G member 5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H222; Mouse: Q99PE8; Rat: Q99PE7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATP-binding cassette sub-family G member 5;Sterolin-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 64240\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239037657267,"sku":"BT-AP14037-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239037690035,"sku":"BT-AP14037-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239037722803,"sku":"BT-AP14037-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7b991abb-06f1-4253-a61f-98b233887a4a.png?v=1769388252","url":"https:\/\/afsbio.com\/products\/abcg5-polyclonal-antibody-bt-ap14037","provider":"AFSBio Inc.","version":"1.0","type":"link"}