{"product_id":"abflo®-450-rabbit-anti-human-monkey-cd4-monoclonal-antibody-a26523","title":"ABflo® 450 Rabbit anti-Human\/Monkey CD4 Monoclonal Antibody - A26523","description":"\u003cp\u003eABflo® 450 Rabbit anti-Human\/Monkey CD4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26523-100, A26523-200, A26523-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human, Cynomolgus\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 51kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 920\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01730\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: T4; IMD79; Leu-3; OKT4D; CD4mut\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Inflammation, CDs, T Cell Receptor Signaling Pathway, Stem Cells, Hematopoietic Progenitors\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CD4\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 450. Ex:406nm. Em:445nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC5142-01\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189292556467,"sku":"A26523-100","price":417.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189292589235,"sku":"A26523-200","price":711.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189292622003,"sku":"A26523-500","price":1313.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_f310c4b8-be58-4c1f-b143-2001ec2424ab.png?v=1766420952","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-450-rabbit-anti-human-monkey-cd4-monoclonal-antibody-a26523","provider":"AFSBio Inc.","version":"1.0","type":"link"}