{"product_id":"abflo®-488-rabbit-anti-4-hydroxynonenal-monoclonal-antibody-a26080","title":"ABflo® 488 Rabbit anti-4-Hydroxynonenal Monoclonal Antibody - A26080","description":"\u003cp\u003eABflo® 488 Rabbit anti-4-Hydroxynonenal Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26080-100, A26080-200, A26080-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: 4-hydroxy-2-nonenal (4-hydroxynonenal, 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS). It non-enzymatically forms stable protein adducts with histidine, lysine, and cysteine side chains that have been used as biomarkers for oxidative damage in cells. Conditions where 4-HNE immunoreactivity has been observed include include inflammation, neurodegenerative diseases, and ischemic damage to the heart and brain.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Other Modified Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC (intra)\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Species independent\u003cbr\u003e\n  \u003cbr\u003e\nImmunogen: Chemical compounds corresponding to 4-Hydroxynonenal.\u003cbr\u003e\n   \u003cbr\u003e\nAlternate Names: 4-HNE\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Oxidative Stress\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: 4-HNE\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC70314\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189163385011,"sku":"A26080-100","price":742.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189163417779,"sku":"A26080-200","price":1229.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189163450547,"sku":"A26080-500","price":1971.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b3920d10-8d62-41d5-89b6-7469e02f069c.png?v=1766418865","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-4-hydroxynonenal-monoclonal-antibody-a26080","provider":"AFSBio Inc.","version":"1.0","type":"link"}