{"product_id":"abflo®-488-rabbit-anti-human-cd27-monoclonal-antibody-a22063","title":"ABflo® 488 Rabbit anti-Human CD27 Monoclonal Antibody - A22063","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human CD27 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A22063-100, A22063-200, A22063-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8\/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 29kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 939\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P26842\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: T14; S152; Tp55; TNFRSF7; S152. LPFS2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor immunology, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway, Stem Cells, Hematopoietic Progenitors\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CD27\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC54542\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189170397363,"sku":"A22063-100","price":406.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189170430131,"sku":"A22063-200","price":672.0,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189170462899,"sku":"A22063-500","price":1075.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_82cf9a8f-e2dd-474b-b9ed-534cfe55dff0.png?v=1766418984","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-cd27-monoclonal-antibody-a22063","provider":"AFSBio Inc.","version":"1.0","type":"link"}