{"product_id":"abflo®-488-rabbit-anti-human-cytokeratin-8-monoclonal-antibody-a23018","title":"ABflo® 488 Rabbit anti-Human Cytokeratin 8 Monoclonal Antibody - A23018","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human Cytokeratin 8 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A23018-100, A23018-200, A23018-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC (intra)\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 53kDa\/56kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3856\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05787\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: K8; KO; CK8; CK-8; CYK8; K2C8; CARD2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Intermediate Filaments\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KRT8\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC58354\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189186945203,"sku":"A23018-100","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189186977971,"sku":"A23018-200","price":338.8,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189187010739,"sku":"A23018-500","price":543.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_28c8c092-d120-4f16-acb1-6b7d01067277.png?v=1766419235","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-cytokeratin-8-monoclonal-antibody-a23018","provider":"AFSBio Inc.","version":"1.0","type":"link"}