{"product_id":"abflo®-488-rabbit-anti-human-desmoglein-3-pva-monoclonal-antibody-a26590","title":"ABflo® 488 Rabbit anti-Human Desmoglein 3\/PVA Monoclonal Antibody - A26590","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human Desmoglein 3\/PVA Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26590-100, A26590-200, A26590-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 108kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1830\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P32926\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PVA; ABOLM; CDHF6\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cadherins, Cytoskeleton, Extracellular Matrix\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: DSG3\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC69331\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189296816307,"sku":"A26590-100","price":669.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189296849075,"sku":"A26590-200","price":1134.0,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189296881843,"sku":"A26590-500","price":2097.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2649611d-c6ad-48ad-8431-ee71160b9e7d.png?v=1766421018","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-desmoglein-3-pva-monoclonal-antibody-a26590","provider":"AFSBio Inc.","version":"1.0","type":"link"}