{"product_id":"abflo®-488-rabbit-anti-human-monkey-pd-1-cd279-monoclonal-antibody-a25732","title":"ABflo® 488 Rabbit anti-Human\/Monkey PD-1\/CD279 Monoclonal Antibody - A25732","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human\/Monkey PD-1\/CD279 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25732-100, A25732-200, A25732-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human, Cynomolgus\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 32kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5133\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15116\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: PDCD1\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC64145\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189250678963,"sku":"A25732-100","price":263.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189250711731,"sku":"A25732-200","price":445.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189250744499,"sku":"A25732-500","price":809.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_52f75b64-49be-4063-adae-41d693118f0b.png?v=1766420294","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-monkey-pd-1-cd279-monoclonal-antibody-a25732","provider":"AFSBio Inc.","version":"1.0","type":"link"}