{"product_id":"abflo®-488-rabbit-anti-human-mouse-integrin-alpha-5-itga5-cd49e-monoclonal-antibody-a22771","title":"ABflo® 488 Rabbit anti-Human\/Mouse Integrin alpha 5 (ITGA5\/CD49e) Monoclonal Antibody - A22771","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human\/Mouse Integrin alpha 5 (ITGA5\/CD49e) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A22771-100, A22771-200, A22771-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 115kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3678\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P08648\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FNRA; CD49e; VLA-5; VLA5A\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ITGA5\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC58294\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189179932851,"sku":"A22771-100","price":305.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189179965619,"sku":"A22771-200","price":501.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189179998387,"sku":"A22771-500","price":795.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_32f09e34-2542-4237-9e0f-1a4f4cb1cea6.png?v=1766419129","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-mouse-integrin-alpha-5-itga5-cd49e-monoclonal-antibody-a22771","provider":"AFSBio Inc.","version":"1.0","type":"link"}