{"product_id":"abflo®-488-rabbit-anti-human-tlr1-monoclonal-antibody-a26257","title":"ABflo® 488 Rabbit anti-Human TLR1 Monoclonal Antibody - A26257","description":"\u003cp\u003eABflo® 488 Rabbit anti-Human TLR1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26257-100, A26257-200, A26257-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and\/or from alternative splicing, have been noted for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 90kDa Immunogen: Synthetic peptide.\u003c\/p\u003e \n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7096\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15399\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TIL; CD281; rsc786; TIL. LPRS5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Immunology Inflammation, CDs, NF-kB Signaling Pathway, Toll-like Receptor Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, TLR Signaling\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: TLR1\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC68825\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189278466227,"sku":"A26257-100","price":417.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189278498995,"sku":"A26257-200","price":711.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189278531763,"sku":"A26257-500","price":1313.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_ed8f3b1a-d1d6-41d4-b41d-62ac14b93fa8.png?v=1766420732","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-human-tlr1-monoclonal-antibody-a26257","provider":"AFSBio Inc.","version":"1.0","type":"link"}